Pawan Kalyan married Nandini in 1997; they separated and divorced in 2008. He married actress Renu Desai, his co-star in Badri and Johnny, in January 2009; they have two children and divorced in 2012, and Renu Desai has said they remain on friendly terms.
In September 2013 he married Anna Lezhneva, a Russian citizen, under the Special Marriage Act in Hyderabad; they have two children. On 9–10 November 2026 the couple announced in a joint statement that they had decided to separate by mutual understanding, would remain responsible parents and asked for privacy.
He is the uncle of actors Ram Charan, Allu Arjun, Varun Tej, Sai Durgha Tej and Panja Vaisshnav Tej, and is known as an avid reader.
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